Advances in Clinical Medical Research http://acmrjournal.com/index.php/acmr <p><strong>Advances in Clinical Medical Research (ACMR)</strong> is an open-access, freely accessible, online and print quarterly peer-reviewed international journal publishes a wide spectrum of advanced research on all medical specialties including ethical and social issues. ACMR is a gateway to enlighten the latest research/issues happening all around the world of medical and health sciences.</p> Advances in Clinical Medical Research 2 Oakfield Place, St. Paul's Road, Clifton, Bristol, England, United Kingdom- BS8 2BJ Phone: +44-7833277351 en-US Advances in Clinical Medical Research 2635-0815 Load Tests of the Renal form of Primary Hyperparathyroidism in Children http://acmrjournal.com/index.php/acmr/article/view/50 <p>After the introduction of calcium chloride (12.4 mg/kg) examined the levels in the blood at 20 and 120 minutes. The calcium content in a comparison group of children after 120 minutes returned to the baseline, in patients with a renal form of primary hyperparathyroidism its level was greater than 1.3 times. The test was sensitive and provided an opportunity to reveal hypercalcemia in 39 children who had been the normo- and hypocalcemia. The impaired renal function had no effect on the significance of the test. Osmotic hypertension develops under the influence of hypertonic sodium chloride. In osmotic diuresis, the excretions of calcium and sodium cations are interdependent.&nbsp; Increasing sodium in the loops of Henle and distal renal tubules stimulates sodium excretion, decreased reabsorption, which leads to increased levels of calcium in the daily urine in children with primary hyperparathyroidism. Test with sodium chloride made it possible to detect hypercalciuria in 12 (21.43%) children who have had normal levels of calcium in urine.</p> Abdusattor Akhatovich Nasirov Bayakhmedov Fathulla Faizievich Copyright (c) 2022 Author https://creativecommons.org/licenses/by/4.0/ 2022-12-04 2022-12-04 3 4 1 3